Showing posts with label Apoptosis. Show all posts
Showing posts with label Apoptosis. Show all posts

Monday, January 10, 2011

Pectasol-C and Cimetidine are effective at keeping cancer at bay

I just had my mastectomy. My scans had shown my tumor enlarging in size after nearly 3 years of weekly Taxol. The Taxol was stopped and I had my surgery 4 weeks later. During that month, the tumor enlarged rapidly in size - I could actually see it enlarging day by day.

My awesome breast surgeon, Helena Chang, director of the Revlon UCLA Breast Center, got the entire tumor out with clean margins and even got the surgical site closed without a skin flap.

The surgical pathology report on the tumor showed it scored 8/9 on an aggressiveness score and showed minimal chemo effect, only 5% of tumor cells showed apoptosis.

I have lived 3 years now with a very aggressive cancer. I'm not cured but I am certain I will not die from this. I keep searching for new ways to treat the underlying fungal infection as it develops resistance to each new treatment. Conventional medicine has been absolutely necessary for my survival, but it is the alternative treatments and antifungal medicines that have saved me. This aggressive cancer would have killed me 2 years ago without IV Caspofungin and Chinese herbs.

Next I start radiation to the surgical site to clean up residual disease in the area.

Microscopic disease in my body beyond the surgical site is not being treated at this time. This is very dangerous given the aggressiveness of this disease. I requested Tamoxifen therapy during radiation until I start chemotherapy again. My wonderful oncologist agreed to this! It's the perfect drug because it's a potent antifungal agent, the real reason it's effective against breast cancer. It will keep metastases from developing while I'm waiting to restart chemo.

As soon as I started Tamoxifen, little stinging pains that had started in different places in my body immediately stopped. I believe it will be very effective in preventing metastases at this time. I would prefer to continue taking it while I'm on chemo - the infection causing the cancerous transformation would be treated at the same time as the cancer, an effective 1-2 punch. But at this time, Tamoxifen with chemo isn't considered safe because of the increased risk of blood clots.

Before my mastectomy I started taking Cimetidine (Tagamet), an over-the-counter stomach acid reducer. It's been known for years in alternative medicine to block the communication between cancer cells. Infectious organisms, including fungi, are known to communicate through chemical signals so the entire colony can act like a unit, like the Republican party. This is the reason resistance to treatment develops so quickly. I've read that when a primary tumor is surgically removed, the metastases immediately flare up and grow even more aggressively. I believe that reaction results from communication between infectious organisms - when the chemical signals from the largest tumor disappear, the remaining organisms are stimulated to grow even more aggressively to overcome the loss and insure the survival of the colony despite the loss.

So I started Cimetidine pre-op to prevent the flare-up when my primary tumor was removed. I also wanted to slow the growth of any metastases while I am off chemo. Before the surgery, the pain in my breast from the tumor had worsened steadily. When I took the Cimetidine, the pain completely stopped, but would come back with a vengeance 23 hours after the last dose - an intense burning pain, like the nasty buggers were trying to make up for lost time. I'm taking the Cimetidine every 12 hours until I restart chemo to prevent any flare-up when the organisms in the surgical site are fried by the radiation.

Pectasol-C is an absolutely brilliant compound with multiple benefits and it's completely safe. It is citrus pectin that has been broken into pieces small enough to absorbed through the intestinal wall into the blood stream. It has 3 important benefits:

1. Heavy metal chelation - very effective in the gut but also should chelate heavy metals in the blood since it is absorbed into the bloodstream.
2. Heals leaky gut - beneficial to prevent new allergies and heal the intestinal wall of breaks caused by toxic microorganisms in the gut. Should be beneficial for irritable bowel, Crohn's and ulcerative colitis.
3. Turns programmed cell death back on in cancer cells. When fungi infect cells, they shut off programmed cell death (apoptosis), the signals that tell the cell it's time to die. Without apoptosis, the cells become immortal and divide uncontrollably, i.e. become cancer. Researchers at Columbia University recently announced their findings on the effect of Pectasol-C on prostate cancer cells. They grew prostate cancer cells in petri dishes and added Pectasol-C and found that apoptosis was turned back on in these cells, resulting in a 54% kill rate in these cells, a strongly significant effect.

Both prostate and breast cancers have been known for years to respond to Pectasol. All of the hormone dependent cancers should respond as well, since they likely are caused by fungi, e.g. colon, melanoma, uterine, bladder.

I am using cimetidine and Pectasol-C along with Tamoxifen at least until I restart chemo in 2 months. I feel really excited and optimistic based on my immediate improvement in my general state of health and lack of side effects. The integrative medicine I am using as an adjunct to conventional treatment is benign and based on actual physiology and solid medical research.

I plan to continue to astonish cancer doctors with my survival and excellent condition for years to come.

Sunday, February 7, 2010

Every Cancer Begins As An Infection

I am certain that all cancers begin as infections. The medical education I received at the University of Chicago and the experiences I've had as a Stage 4 breast cancer patient have made that crystal clear to me. Every mystery about cancer, everything we do not understand, is explained and crystal clear when you look at cancer as the result of an infection altering the body's functions.

I've started a literature search online to find the mechanism by which a fungal infection could trigger carcinogenesis (the "start" of cancer). The very first reference I found had the answer, a review entitled, "Fungal Invasion of Normally Non-Phagocytic Host Cells," by Scott G. Filler and Donald C. Sheppard, PLoS Pathog 2(12): e129.doi:10.1371/journal.ppat.0020129.

In this review, the authors describe how fungal organisms trigger healthy cells like skin and lung cells to absorb them. This means that in any fungal infection, the infecting organisms are located INSIDE the cells, where they can disrupt a cell's normal functions.

In addition, the review describes how some fungi block apoptosis in the cells they infect. Apoptosis is programmed cell death, the chemical signals that tell a cell when it's time to die, that give cells a definite lifespan. Without programmed cell death, the cells become immortal, multiplying out of control. Loss of apoptosis is the very heart of carcinogenesis.

An example given in the review describes how Aspergillus fumigatus (tree mold), a common human pathogen, infects lung cells (type II pneumocytes) when the mold spores are inhaled and how Aspergillus blocks apoptosis in the lung cells. This is a clear, simple mechanism for the start of lung cancer. Everyone inhales mold spores, probably on a daily basis. When the spores are absorbed into our lung cells and apoptosis is blocked, the cells are transformed into cancer cells. Our immune systems detect the altered cells and destroy them before they can multiply into tumors. Smokers are unable to destroy these cancer cells because their physical defenses and immune systems are damaged by the tar and nicotine they inhale, so the cancer cells multiply into malignant tumors.

I am dumbfounded that this information is already in the literature but has been overlooked by researchers. EVERYONE wants to find the cure for cancer and the assumption that cancer is caused by defective genes has NOT led to a cure despite decades of research. The death rate due to cancer has never improved! The answer is under our noses and the basic facts are already in the literature.

Every cancer begins as an infection. Some start as viral infections, like cervical cancer, some start as fungal infections, like my breast cancer. Other types of human pathogens may cause cancer as well. We'll know when we start looking for the causative organisms in malignant tissue specimens.

The cure for the most common types of cancer is so close! Medications that cure these infections already exist and are already FDA-approved. We just need to make the connection so these effective medications can be used to save cancer patients!

If you know any medical researchers or cancer activists you believe would be interested in what I'm saying and would want to pursue it, PLEASE forward this blog to them or email me so I can contact them.

Cancer patients are dying every day. We need to begin administering effective anti-infective medication to them ASAP. Every day lost means more lives lost.